Approaches to identify, clone, and express symbiont bioactive metabolite genes
Document Type
Article
Publication Date
2004
Abstract
This review discusses approaches to identify, clone, and express bioactive metabolite genes from symbionts of marine invertebrates. Criteria for proving symbiotic origin of bioactive metabolites are presented, followed by a comprehensive, practically-oriented overview of techniques to be applied. The Bugula neritina/Endobugula sertula association is used as a primary example, but other symbioses are discussed. Thirty-six compounds are presented and 111 references are cited.
Recommended Citation
Hildebrand, M., Waggoner, L.E., Lim, G.E., Sharp, K.H., Ridley, C.P., & Haygood, M.G. (2004). Approaches to identify, clone and express symbiont bioactive metabolite genes. Natural Products Reports, 21(1), 122-142.
Comments
Published in: Natural Products Reports, vol.21, issue 1, 2004.