Monitoring HIFU lesion formation in vitro via the driving voltage

Document Type

Conference Proceeding

Publication Title

AIP Conference Proceedings

Publication Date

5-8-2006

Abstract

During insonation of tissue and tissue-mimicking materials with high-intensity focused ultrasound (HIFU), bubbles formed at or near the focus of the HIFU source have been shown to cause fluctuations in the HIFU driving voltage and current amplitudes. In this paper, we report the results of an investigation of these oscillations in an in vitro system - polyacrylamide phantoms with bovine serum albumin (BSA). The fluctuations in the HIFU driving voltage were interpreted to be the result of constructive and destructive interference at the transducer face caused by the incident HIFU and backscattered ultrasound from the bubbles in the lesion. Interpreting the fluctuations in this manner can lead to a determination of the location of the advancing interface of the bubbly lesion as it moves towards the HIFU transducer during CW insonation. © 2006 American Institute of Physics.

Volume

829

First Page

293

Last Page

297

DOI

10.1063/1.2205484

ISSN

0094243X

E-ISSN

15517616

ISBN

073540321X,9780735403215

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