Monitoring HIFU lesion formation in vitro via the driving voltage
AIP Conference Proceedings
During insonation of tissue and tissue-mimicking materials with high-intensity focused ultrasound (HIFU), bubbles formed at or near the focus of the HIFU source have been shown to cause fluctuations in the HIFU driving voltage and current amplitudes. In this paper, we report the results of an investigation of these oscillations in an in vitro system - polyacrylamide phantoms with bovine serum albumin (BSA). The fluctuations in the HIFU driving voltage were interpreted to be the result of constructive and destructive interference at the transducer face caused by the incident HIFU and backscattered ultrasound from the bubbles in the lesion. Interpreting the fluctuations in this manner can lead to a determination of the location of the advancing interface of the bubbly lesion as it moves towards the HIFU transducer during CW insonation. © 2006 American Institute of Physics.
Thomas, C., Farny, C., Wu, T., Holt, R., & Roy, R. (2006). Monitoring HIFU lesion formation in vitro via the driving voltage. AIP Conference Proceedings, 829, 293-297. https://doi.org/10.1063/1.2205484